STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KGM_202858Lethal. (639 aa)    
Predicted Functional Partners:
KGM_214746
DNA damage-binding protein 1.
    
 0.992
KGM_215697
Cullin-4B; Belongs to the cullin family.
    
 0.989
KGM_205849
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.980
KGM_213538
DNA replication factor Cdt1.
   
 
 0.976
KGM_214148
Putative Cdc6.
   
  
 0.959
KGM_215634
Acidic nucleoplasmic DNA-binding protein 1.
   
  
 0.957
KGM_211860
Ring box protein.
    
 0.923
KGM_214279
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
   
  
 0.917
KGM_210425
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
  
 0.910
KGM_209516
Sensitized chromosome inheritance modifier 19.
   
  
 0.899
Your Current Organism:
Danaus plexippus
NCBI taxonomy Id: 278856
Other names: D. plexippus plexippus, Danaus plexippus plexippus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.