STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4Z1JI242-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (457 aa)    
Predicted Functional Partners:
A0A4Z1J0E0
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
A0A4Z1K0M0
Transket_pyr domain-containing protein.
 0.999
A0A4Z1KGM7
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.996
A0A4Z1K0S7
Dihydrolipoyl dehydrogenase.
 
 
 0.984
A0A4Z1JDD5
Uncharacterized protein.
 
 0.973
A0A4Z1JCR4
Uncharacterized protein.
 
 0.971
A0A4Z1JNY4
Lipoyl-binding domain-containing protein.
  
 0.965
A0A4Z1JLJ0
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.944
A0A4Z1K1K8
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 0.944
A0A4Z1JE48
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.943
Your Current Organism:
Botrytis elliptica
NCBI taxonomy Id: 278938
Other names: B. elliptica
Server load: low (16%) [HD]