STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4Z1JQ03Uncharacterized protein. (1232 aa)    
Predicted Functional Partners:
A0A4Z1JRV0
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 0.970
A0A4Z1J4H2
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.969
A0A4Z1J7Z8
RMI1_N domain-containing protein.
    
 0.962
A0A4Z1JYA3
Uncharacterized protein.
    
 0.955
A0A4Z1JAK4
3'-5' exonuclease domain-containing protein.
   
 0.948
A0A4Z1JP43
ERCC4 domain-containing protein.
    
 0.935
A0A4Z1K3Z1
Uncharacterized protein.
   
 0.928
A0A4Z1KGP3
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.928
A0A4Z1K3M2
MPN domain-containing protein.
    
 0.927
A0A4Z1JA78
Uncharacterized protein.
    
 
 0.916
Your Current Organism:
Botrytis elliptica
NCBI taxonomy Id: 278938
Other names: B. elliptica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.