STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (515 aa)    
Predicted Functional Partners:
OAS38736.1
Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.991
OAS42332.1
Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
OAS40755.1
Pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.939
pyrB
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.938
hpt
Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.929
argG
Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 
 0.916
surE
5'/3'-nucleotidase SurE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.911
OAS42211.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.900
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.896
OAS38986.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.892
Your Current Organism:
Opitutaceae bacterium TAV4
NCBI taxonomy Id: 278959
Other names: O. bacterium TAV4
Server load: low (20%) [HD]