STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrhLABC transporter; Putative acyltransferase. (626 aa)    
Predicted Functional Partners:
yfiX
Conserved membrane protein YfiX; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
   
 0.665
yrhM
YrhM; Similar to anti-sigma factor.
 
  
 0.614
sigV
RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-V); Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.547
tuaE
TuaE.
 
   
 0.467
dltB
DltB; Could be involved in the transport of activated D-alanine through the membrane.
 
   
 0.460
ydgK
Putative Drug resistance transporter; Bcr/CflA subfamily.
  
    0.450
yjgD
Hypothetical protein.
  
     0.444
yhcR
Nucleic acid-binding hydrolase YhcR.
  
  
 0.418
dhbF
DhbF.
     
 0.413
BL03427
Hypothetical protein; Molecular Function: DNA binding, Cellular Component: nucleus.
   
  
 0.404
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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