STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yabADnaA and DnaN interacting protein containing domain DUF972- YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family. (120 aa)    
Predicted Functional Partners:
holB
DNA polymerase III (delta' subunit).
 
    0.882
dnaN
DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation o [...]
  
 
 
 0.849
yaaT
Putative signal peptidase II YaaT; Involved in the transduction of signals to the phosphorelay for initiation of sporulation, similar to signal peptidase II, contains PSP1_C terminal domain.
  
    0.849
yaaR
Conserved hypothetical protein YaaR.
  
    0.825
dnaA
DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.799
yaaQ
YaaQ.
  
    0.797
yabB
Conserved hypothetical protein containing SAM (and some other nucleotide) binding motif YabB.
  
  
 0.761
yabC
Putative methyltransferase YabC containing domain UPF0011; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
    0.742
yazA
Putative Excinuclease ABC, C subunit, N-terminal YazA; Belongs to the UPF0213 family.
  
    0.740
yaaO
Putative Orn/Lys/Arg decarboxylase, C-terminal YaaO; Probable lysine decarboxylase.
  
    0.674
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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