STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yabADnaA and DnaN interacting protein containing domain DUF972- YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family. (120 aa)    
Predicted Functional Partners:
holB
DNA polymerase III (delta' subunit).
 
    0.856
yaaT
Putative signal peptidase II YaaT; Involved in the transduction of signals to the phosphorelay for initiation of sporulation, similar to signal peptidase II, contains PSP1_C terminal domain.
  
    0.815
dnaN
DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation o [...]
  
 
 
 0.779
yaaR
Conserved hypothetical protein YaaR.
  
    0.769
yaaQ
YaaQ.
  
    0.739
dnaA
DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.724
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.693
yabC
Putative methyltransferase YabC containing domain UPF0011; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
    0.661
yabB
Conserved hypothetical protein containing SAM (and some other nucleotide) binding motif YabB.
  
    0.660
yazA
Putative Excinuclease ABC, C subunit, N-terminal YazA; Belongs to the UPF0213 family.
  
    0.658
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.