| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BL00880 | BL03503 | BL00880 | BL03503 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | 0.568 |
| BL00880 | clpP | BL00880 | BL03605 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | 0.661 |
| BL00880 | clpP2 | BL00880 | BL05355 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | ATP-dependentprotease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.668 |
| BL00880 | clpX | BL00880 | BL00619 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.975 |
| BL00880 | dfrA | BL00880 | BL03300 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.458 |
| BL00880 | groEL | BL00880 | BL03283 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | Class I heat-shock protein (chaperonin); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.660 |
| BL00880 | lonA | BL00880 | BL00621 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | Class III heat-shock ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.503 |
| BL03503 | BL00880 | BL03503 | BL00880 | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | 0.568 |
| BL03503 | clpP | BL03503 | BL03605 | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | 0.660 |
| BL03503 | clpP2 | BL03503 | BL05355 | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | ATP-dependentprotease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.666 |
| BL03503 | clpX | BL03503 | BL00619 | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.976 |
| BL03503 | dfrA | BL03503 | BL03300 | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.458 |
| BL03503 | groEL | BL03503 | BL03283 | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | Class I heat-shock protein (chaperonin); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.660 |
| BL03503 | lonA | BL03503 | BL00621 | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | Class III heat-shock ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.503 |
| clpP | BL00880 | BL03605 | BL00880 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | 0.661 |
| clpP | BL03503 | BL03605 | BL03503 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | ATP-dependent protease proteolytic subunit (class III heat-shock protein); Belongs to the peptidase S14 family. | 0.660 |
| clpP | clpP2 | BL03605 | BL05355 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | ATP-dependentprotease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.547 |
| clpP | clpX | BL03605 | BL00619 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.996 |
| clpP | dfrA | BL03605 | BL03300 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.458 |
| clpP | ftsH | BL03605 | BL00852 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | Cell-division protein and general stress protein (class III heat-shock); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.765 |
