| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| clpE | clpQ | BL03640 | BL01278 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | 0.677 |
| clpE | clpX | BL03640 | BL00619 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.572 |
| clpE | clpY | BL03640 | BL01277 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Two-component ATP-dependent protease (N-terminal serine protease); ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | 0.783 |
| clpE | dnaK | BL03640 | BL02097 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.980 |
| clpE | ftsH | BL03640 | BL00852 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Cell-division protein and general stress protein (class III heat-shock); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.454 |
| clpE | groEL | BL03640 | BL03283 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Class I heat-shock protein (chaperonin); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.790 |
| clpE | grpE | BL03640 | BL02095 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Heat-shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.882 |
| clpE | htpG | BL03640 | BL00247 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity. | 0.849 |
| clpE | lonA | BL03640 | BL00621 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Class III heat-shock ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.750 |
| clpQ | clpE | BL01278 | BL03640 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | 0.677 |
| clpQ | clpX | BL01278 | BL00619 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.760 |
| clpQ | clpY | BL01278 | BL01277 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | Two-component ATP-dependent protease (N-terminal serine protease); ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | 0.999 |
| clpQ | dnaK | BL01278 | BL02097 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | Class I heat-shock protein (molecular chaperone); Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.736 |
| clpQ | ftsH | BL01278 | BL00852 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | Cell-division protein and general stress protein (class III heat-shock); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.551 |
| clpQ | groEL | BL01278 | BL03283 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | Class I heat-shock protein (chaperonin); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.872 |
| clpQ | grpE | BL01278 | BL02095 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | Heat-shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | 0.909 |
| clpQ | htpG | BL01278 | BL00247 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity. | 0.876 |
| clpQ | lonA | BL01278 | BL00621 | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | Class III heat-shock ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.854 |
| clpX | clpE | BL00619 | BL03640 | ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | 0.572 |
| clpX | clpQ | BL00619 | BL01278 | ATP-dependent Clp protease ATP-binding subunit (class III heat-shock protein); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. | 0.760 |
