| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BL03089 | mgsA | BL03089 | BL02757 | Putative iron-binding oxidoreductase. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.913 |
| BL03089 | ytbE | BL03089 | BL00471 | Putative iron-binding oxidoreductase. | Aldo/keto reductase YtbE. | 0.900 |
| BL03089 | yvgN | BL03089 | BL00701 | Putative iron-binding oxidoreductase. | Putative 2,5-diketo-D-gluconic acid reductase YvgN. | 0.900 |
| ilvA | sdaAA | BL03302 | BL02310 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.921 |
| ilvA | sdaAB | BL03302 | BL02309 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-serine dehydratase (beta chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.935 |
| ilvA | trpA | BL03302 | BL02770 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Tryptophan synthase (alpha subunit); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.914 |
| ilvA | ytbE | BL03302 | BL00471 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Aldo/keto reductase YtbE. | 0.807 |
| ilvA | yvcT | BL03302 | BL03603 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Probable 2-ketogluconate reductase YvcT; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.813 |
| ilvA | yvgN | BL03302 | BL00701 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Putative 2,5-diketo-D-gluconic acid reductase YvgN. | 0.807 |
| ilvA | ywbC | BL03302 | BL03939 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Putative lyase YwbC. | 0.800 |
| ilvA | yyaH | BL03302 | BL01952 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Putative Glyoxalase family protein. | 0.823 |
| mgsA | BL03089 | BL02757 | BL03089 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | Putative iron-binding oxidoreductase. | 0.913 |
| mgsA | ytbE | BL02757 | BL00471 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | Aldo/keto reductase YtbE. | 0.904 |
| mgsA | yvgN | BL02757 | BL00701 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | Putative 2,5-diketo-D-gluconic acid reductase YvgN. | 0.904 |
| sdaAA | ilvA | BL02310 | BL03302 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.921 |
| sdaAA | sdaAB | BL02310 | BL02309 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | L-serine dehydratase (beta chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.999 |
| sdaAA | trpA | BL02310 | BL02770 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase (alpha subunit); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.925 |
| sdaAA | ytbE | BL02310 | BL00471 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Aldo/keto reductase YtbE. | 0.800 |
| sdaAA | yvcT | BL02310 | BL03603 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Probable 2-ketogluconate reductase YvcT; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.804 |
| sdaAA | yvgN | BL02310 | BL00701 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative 2,5-diketo-D-gluconic acid reductase YvgN. | 0.800 |
