| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BL00713 | exuR | BL00713 | BL00710 | Glycoside Hydrolase Family 28; Belongs to the glycosyl hydrolase 28 family. | Transcriptional regulator. | 0.640 |
| BL00713 | uxaA | BL00713 | BL00712 | Glycoside Hydrolase Family 28; Belongs to the glycosyl hydrolase 28 family. | Altronate hydrolase. | 0.840 |
| BL00713 | uxaB | BL00713 | BL00711 | Glycoside Hydrolase Family 28; Belongs to the glycosyl hydrolase 28 family. | Tagaturonate reductase (altronate oxidoreductase). | 0.866 |
| BL00713 | uxaC | BL00713 | BL00708 | Glycoside Hydrolase Family 28; Belongs to the glycosyl hydrolase 28 family. | Glucuronate isomerase. | 0.739 |
| BL00713 | yjmB | BL00713 | BL00709 | Glycoside Hydrolase Family 28; Belongs to the glycosyl hydrolase 28 family. | Putative Sodium:galactoside symporter. | 0.545 |
| exuR | BL00713 | BL00710 | BL00713 | Transcriptional regulator. | Glycoside Hydrolase Family 28; Belongs to the glycosyl hydrolase 28 family. | 0.640 |
| exuR | uxaA | BL00710 | BL00712 | Transcriptional regulator. | Altronate hydrolase. | 0.622 |
| exuR | uxaB | BL00710 | BL00711 | Transcriptional regulator. | Tagaturonate reductase (altronate oxidoreductase). | 0.647 |
| exuR | uxaC | BL00710 | BL00708 | Transcriptional regulator. | Glucuronate isomerase. | 0.613 |
| exuR | yjmB | BL00710 | BL00709 | Transcriptional regulator. | Putative Sodium:galactoside symporter. | 0.594 |
| galK | uxaC | BL00191 | BL00708 | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | Glucuronate isomerase. | 0.632 |
| galK | yjmB | BL00191 | BL00709 | Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. | Putative Sodium:galactoside symporter. | 0.474 |
| ndk | nrdE | BL02781 | BL01192 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.805 |
| ndk | yjmB | BL02781 | BL00709 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative Sodium:galactoside symporter. | 0.549 |
| ndk | ywtG | BL02781 | BL01181 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Sugar transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | 0.460 |
| nrdE | ndk | BL01192 | BL02781 | Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.805 |
| nrdE | thyA | BL01192 | BL02642 | Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthase A; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.868 |
| nrdE | yjmB | BL01192 | BL00709 | Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Putative Sodium:galactoside symporter. | 0.552 |
| nrdE | ywtG | BL01192 | BL01181 | Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Sugar transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. | 0.520 |
| thyA | nrdE | BL02642 | BL01192 | Thymidylate synthase A; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.868 |