| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| rsbW | sigB | BL02207 | BL02208 | Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | RNA polymerase sigma-37 factor (sigma-B); Belongs to the sigma-70 factor family. | 0.999 |
| rsbW | sigF | BL02207 | BL00778 | Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.931 |
| rsbW | spoIIAA | BL02207 | BL00776 | Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | Anti-anti-sigma factor (antagonist of SpoIIAB); Belongs to the anti-sigma-factor antagonist family. | 0.880 |
| rsbW | spoIIGA | BL02207 | BL02254 | Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | Protease SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.462 |
| sigB | rsbW | BL02208 | BL02207 | RNA polymerase sigma-37 factor (sigma-B); Belongs to the sigma-70 factor family. | Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.999 |
| sigB | spoIIAA | BL02208 | BL00776 | RNA polymerase sigma-37 factor (sigma-B); Belongs to the sigma-70 factor family. | Anti-anti-sigma factor (antagonist of SpoIIAB); Belongs to the anti-sigma-factor antagonist family. | 0.907 |
| sigB | spoIIAB | BL02208 | BL00777 | RNA polymerase sigma-37 factor (sigma-B); Belongs to the sigma-70 factor family. | Anti-sigma factor (antagonist of sigma-F) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.868 |
| sigB | spoIIGA | BL02208 | BL02254 | RNA polymerase sigma-37 factor (sigma-B); Belongs to the sigma-70 factor family. | Protease SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.481 |
| sigF | rsbW | BL00778 | BL02207 | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.931 |
| sigF | spoIIAA | BL00778 | BL00776 | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-anti-sigma factor (antagonist of SpoIIAB); Belongs to the anti-sigma-factor antagonist family. | 0.971 |
| sigF | spoIIAB | BL00778 | BL00777 | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma factor (antagonist of sigma-F) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.996 |
| sigF | spoIIE | BL00778 | BL00506 | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Serine phosphatase. | 0.686 |
| sigF | spoIIGA | BL00778 | BL02254 | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Protease SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.736 |
| sigF | spoIIR | BL00778 | BL03984 | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SpoIIR. | 0.749 |
| sigF | spoVAC | BL00778 | BL00781 | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SpoVAC. | 0.903 |
| sigF | spoVAD | BL00778 | BL00782 | RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | SpoVAD. | 0.897 |
| sigG | spoIIAA | BL02256 | BL00776 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-anti-sigma factor (antagonist of SpoIIAB); Belongs to the anti-sigma-factor antagonist family. | 0.782 |
| sigG | spoIIAB | BL02256 | BL00777 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma factor (antagonist of sigma-F) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.898 |
| sigG | spoIIE | BL02256 | BL00506 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Serine phosphatase. | 0.811 |
| sigG | spoIIGA | BL02256 | BL02254 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Protease SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.920 |
