lanM2 protein (Bacillus licheniformis) - STRING interaction network

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lanM2

Lantibiotic modifying enzyme. (1052 aa)

Predicted Functional Partners:

lanA

0.791

lanT

0.715

lanR

0.541

vgb

0.515

lanP

0.479

lchAD

0.445

yjiC

0.444

BL01309

0.440

yesE

0.418

lanM1

0.418

Your Current Organism:

Bacillus licheniformis

NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BL01309	lanM1	BL01309	BL00928	Short-chain dehydrogenase/reductase SDR.	Lantibiotic modifying enzyme.	0.471
BL01309	lanM2	BL01309	BL00948	Short-chain dehydrogenase/reductase SDR.	Lantibiotic modifying enzyme.	0.440
BL01309	vgb	BL01309	BL01635	Short-chain dehydrogenase/reductase SDR.	Putative soluble quinoprotein glucose dehydrogenase protein; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid.	0.582
lanA	lanM1	BL05375	BL00928	Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...]	Lantibiotic modifying enzyme.	0.531
lanA	lanM2	BL05375	BL00948	Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...]	Lantibiotic modifying enzyme.	0.791
lanA	lanP	BL05375	BL00930	Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...]	Intracellular serine protease; Belongs to the peptidase S8 family.	0.582
lanA	lanR	BL05375	BL00932	Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...]	Transcriptional regulator.	0.618
lanM1	BL01309	BL00928	BL01309	Lantibiotic modifying enzyme.	Short-chain dehydrogenase/reductase SDR.	0.471
lanM1	lanA	BL00928	BL05375	Lantibiotic modifying enzyme.	Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...]	0.531
lanM1	lanM2	BL00928	BL00948	Lantibiotic modifying enzyme.	Lantibiotic modifying enzyme.	0.418
lanM1	lanP	BL00928	BL00930	Lantibiotic modifying enzyme.	Intracellular serine protease; Belongs to the peptidase S8 family.	0.881
lanM1	lanR	BL00928	BL00932	Lantibiotic modifying enzyme.	Transcriptional regulator.	0.771
lanM1	lanT	BL00928	BL00929	Lantibiotic modifying enzyme.	Lantibiotic transport protein.	0.917
lanM1	lchAD	BL00928	BL01729	Lantibiotic modifying enzyme.	Thioesterase LchAD.	0.499
lanM1	vgb	BL00928	BL01635	Lantibiotic modifying enzyme.	Putative soluble quinoprotein glucose dehydrogenase protein; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid.	0.539
lanM1	yesE	BL00928	BL00450	Lantibiotic modifying enzyme.	Conserved protein YesE.	0.424
lanM1	yjiC	BL00928	BL00446	Lantibiotic modifying enzyme.	Glycosyl transferase Family 1.	0.470
lanM2	BL01309	BL00948	BL01309	Lantibiotic modifying enzyme.	Short-chain dehydrogenase/reductase SDR.	0.440
lanM2	lanA	BL00948	BL05375	Lantibiotic modifying enzyme.	Lichenicidin prepeptide; Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. When present individually, LchA1 exhibits activity towards L.lactis HP. When combined with LchA2, it displays activity towards a broad spectrum of non-pathogenic and pathogenic Gram-positive bacteria including strains of L.monocytogenes, methicillin-resistant S.aureus, S.pneumoniae and strains of vanco [...]	0.791
lanM2	lanM1	BL00948	BL00928	Lantibiotic modifying enzyme.	Lantibiotic modifying enzyme.	0.418

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