STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yhfJPutative Lipoyltransferase and lipoate-protein ligase. (329 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 
 0.990
ywfL
Conserved protein YwfL; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family.
 
  
 0.977
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
 
 
 0.964
yhfI
Putative hydrolase. conserved hypothetical protein.
  
    0.953
pdhC
Pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit).
 
 0.806
pdhD
Dihydrolipoamide dehydrogenase E3 subunit of both pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes.
 
  
 0.788
bkdB
Branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase).
 
 0.747
acoL
Acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase).
 
  
 0.726
acoC
Acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.725
bfmBC
Branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase).
 
  
 0.711
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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