STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheAPrephenate dehydratase. (285 aa)    
Predicted Functional Partners:
aroA
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3.
 
 0.983
pheB
Chorismate mutase; Belongs to the UPF0735 family.
 
 
 0.941
tyrA
Prephenate dehydrogenase.
 
 0.853
aspB
Aspartate aminotransferase.
 
 
  0.810
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.805
BL03053
Probable transcriptional regulator (AraC/XylS family).
  
 
 0.795
BL02124
Anthranilate phosphoribosyltransferase.
 
 
 0.780
trpE
Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.
 
  
 0.777
ilvH
Acetolactate synthase (acetohydroxy-acid synthase) (small subunit).
 
  
 0.773
trpC
Indol-3-glycerol phosphate synthase; Belongs to the TrpC family.
 
  
 0.755
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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