| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroA | aroF | BL00056 | BL02779 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.998 |
| aroA | aroH | BL00056 | BL02776 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Chorismate mutase (isozymes 1 and 2); Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.966 |
| aroA | dhbC | BL00056 | BL04021 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Isochorismate synthase. | 0.910 |
| aroA | menF | BL00056 | BL02409 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.920 |
| aroA | pabA | BL00056 | BL00859 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Para-aminobenzoate synthase glutamine amidotransferase (subunit B) and anthranilate synthase (subunit II). | 0.939 |
| aroA | pabB | BL00056 | BL00858 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Para-aminobenzoate synthase (subunit A). | 0.906 |
| aroA | pheA | BL00056 | BL01156 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Prephenate dehydratase. | 0.994 |
| aroA | pheB | BL00056 | BL01157 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Chorismate mutase; Belongs to the UPF0735 family. | 0.900 |
| aroA | trpE | BL00056 | BL02775 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. | 0.953 |
| aroA | tyrA | BL00056 | BL02768 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | Prephenate dehydrogenase. | 0.994 |
| aroF | aroA | BL02779 | BL00056 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase and chorismate mutase-isozyme 3. | 0.998 |
| aroF | aroH | BL02779 | BL02776 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase (isozymes 1 and 2); Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.995 |
| aroF | dhbC | BL02779 | BL04021 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Isochorismate synthase. | 0.949 |
| aroF | menF | BL02779 | BL02409 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.928 |
| aroF | pabA | BL02779 | BL00859 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Para-aminobenzoate synthase glutamine amidotransferase (subunit B) and anthranilate synthase (subunit II). | 0.900 |
| aroF | pabB | BL02779 | BL00858 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Para-aminobenzoate synthase (subunit A). | 0.918 |
| aroF | pheA | BL02779 | BL01156 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Prephenate dehydratase. | 0.590 |
| aroF | pheB | BL02779 | BL01157 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Chorismate mutase; Belongs to the UPF0735 family. | 0.900 |
| aroF | trpE | BL02779 | BL02775 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. | 0.975 |
| aroF | tyrA | BL02779 | BL02768 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Prephenate dehydrogenase. | 0.960 |
