| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| kinE | spo0A | BL03536 | BL01518 | Two-component sensor histidine kinase. | Two-component response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.968 |
| kinE | spo0B | BL03536 | BL01158 | Two-component sensor histidine kinase. | Sporulation initiation phosphotransferase. | 0.766 |
| kinE | spo0F | BL03536 | BL03968 | Two-component sensor histidine kinase. | Two-component response regulator. | 0.992 |
| nusG | spo0B | BL05007 | BL01158 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | Sporulation initiation phosphotransferase. | 0.769 |
| nusG | ybxB | BL05007 | BL02799 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | Hypothetical protein with SAM binding motif. | 0.583 |
| nusG | ydbR | BL05007 | BL02197 | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | Probable ATP-dependent RNA helicase YdbR; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | 0.698 |
| obg | spo0B | BL01159 | BL01158 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Sporulation initiation phosphotransferase. | 0.983 |
| obg | spoIVFA | BL01159 | BL00642 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | SpoIVFA. | 0.412 |
| obg | ybxB | BL01159 | BL02799 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Hypothetical protein with SAM binding motif. | 0.783 |
| obg | ydbR | BL01159 | BL02197 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Probable ATP-dependent RNA helicase YdbR; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | 0.515 |
| spo0A | kinE | BL01518 | BL03536 | Two-component response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Two-component sensor histidine kinase. | 0.968 |
| spo0A | spo0B | BL01518 | BL01158 | Two-component response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Sporulation initiation phosphotransferase. | 0.986 |
| spo0A | spo0E | BL01518 | BL03543 | Two-component response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Negative sporulation regulatory phosphatase. | 0.778 |
| spo0A | spo0F | BL01518 | BL03968 | Two-component response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Two-component response regulator. | 0.952 |
| spo0B | kinE | BL01158 | BL03536 | Sporulation initiation phosphotransferase. | Two-component sensor histidine kinase. | 0.766 |
| spo0B | nusG | BL01158 | BL05007 | Sporulation initiation phosphotransferase. | Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. | 0.769 |
| spo0B | obg | BL01158 | BL01159 | Sporulation initiation phosphotransferase. | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.983 |
| spo0B | spo0A | BL01158 | BL01518 | Sporulation initiation phosphotransferase. | Two-component response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.986 |
| spo0B | spo0E | BL01158 | BL03543 | Sporulation initiation phosphotransferase. | Negative sporulation regulatory phosphatase. | 0.763 |
| spo0B | spo0F | BL01158 | BL03968 | Sporulation initiation phosphotransferase. | Two-component response regulator. | 0.999 |