Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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pdhAPyruvate dehydrogenase (E1 alpha subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (371 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase (E1 beta subunit).
 0.999
pdhC
Pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit).
 
 0.999
bkdAB
Branched-chain alpha-keto acid dehydrogenase E1 subunit (2-oxoisovalerate dehydrogenase beta subunit).
 0.998
pdhD
Dihydrolipoamide dehydrogenase E3 subunit of both pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes.
 
 
 0.998
acoB
Acetoin dehydrogenase E1 component (TPP-dependent beta subunit).
 0.997
acoC
Acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.991
acoL
Acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase).
 
 
 0.984
bfmBC
Branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase).
 
 
 0.982
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.956
bkdB
Branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase).
 
 0.927
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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