STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacA2Glycoside Hydrolase Family 42; BL01749 similar to lacA from Bacillus subtilis, named by MDT - PiRa. (690 aa)    
Predicted Functional Partners:
BL02681
Putative glycoside hydrolase family 31; Belongs to the glycosyl hydrolase 31 family.
 
 
 0.780
yesZ
Glycoside hydrolase, family 42; May play a role in the degradation of rhamnogalacturonan derived from plant cell walls.
  
  
 
0.728
ylyB
Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
      
 0.613
lacA
Glycoside Hydrolase Family 42; Hydrolyzes oligosaccharides released by the endo-1,4-beta- galactosidase GalA from arabinogalactan type I, a pectic plant polysaccharide. It is unable to use lactose as a sole carbon source (By similarity). Catalyzes the hydrolysis of lactose to its constituent monosaccharides glucose and galactose. Possesses a low level of transgalactosylation activity for the production of galacto- oligosaccharides (GOS) from lactose; Belongs to the glycosyl hydrolase 42 family.
  
  
 
0.610
bioI
Cytochrome P450 enzyme.
      
 0.610
yvfO
Glyccosyl Hydrolase Family 53; Hydrolyzes the beta-1,4-galactan linkages of arabinogalactan type I, a pectic substance found in plants such as soybeans.
 
  
 0.598
luxS
Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
      
 0.565
yoxA
Conserved hypothetical protein.
  
 
 0.523
apr
Apr; Belongs to the peptidase S8 family.
      
 0.518
BL00280
Glycoside hydrolase family 31; Belongs to the glycosyl hydrolase 31 family.
 
 
 0.500
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.