| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BL02060 | yqgX | BL02060 | BL01575 | Metallo-beta-lactamase/rhodanese-like domain protein. | Conserved protein YqgX. | 0.926 |
| BL02060 | ywbC | BL02060 | BL03939 | Metallo-beta-lactamase/rhodanese-like domain protein. | Putative lyase YwbC. | 0.911 |
| BL02060 | yyaH | BL02060 | BL01952 | Metallo-beta-lactamase/rhodanese-like domain protein. | Putative Glyoxalase family protein. | 0.911 |
| ilvA | sdaAA | BL03302 | BL02310 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.921 |
| ilvA | sdaAB | BL03302 | BL02309 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | L-serine dehydratase (beta chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.935 |
| ilvA | trpB | BL03302 | BL02771 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Tryptophan synthase (beta subunit); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.938 |
| ilvA | ytbE | BL03302 | BL00471 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Aldo/keto reductase YtbE. | 0.807 |
| ilvA | yvcT | BL03302 | BL03603 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Probable 2-ketogluconate reductase YvcT; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.813 |
| ilvA | yvgN | BL03302 | BL00701 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Putative 2,5-diketo-D-gluconic acid reductase YvgN. | 0.807 |
| ilvA | ywbC | BL03302 | BL03939 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Putative lyase YwbC. | 0.800 |
| ilvA | yyaH | BL03302 | BL01952 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Putative Glyoxalase family protein. | 0.823 |
| sdaAA | ilvA | BL02310 | BL03302 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.921 |
| sdaAA | sdaAB | BL02310 | BL02309 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | L-serine dehydratase (beta chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.999 |
| sdaAA | trpB | BL02310 | BL02771 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase (beta subunit); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| sdaAA | ytbE | BL02310 | BL00471 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Aldo/keto reductase YtbE. | 0.800 |
| sdaAA | yvcT | BL02310 | BL03603 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Probable 2-ketogluconate reductase YvcT; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.804 |
| sdaAA | yvgN | BL02310 | BL00701 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative 2,5-diketo-D-gluconic acid reductase YvgN. | 0.800 |
| sdaAA | ywbC | BL02310 | BL03939 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative lyase YwbC. | 0.800 |
| sdaAA | yyaH | BL02310 | BL01952 | L-serine dehydratase (alpha chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative Glyoxalase family protein. | 0.800 |
| sdaAB | ilvA | BL02309 | BL03302 | L-serine dehydratase (beta chain); Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.935 |
