| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BL00252 | yitD | BL00252 | BL02005 | Conserved hypothetical protein. | (2R)-phospho-3-sulfolactate synthase, ComA. | 0.466 |
| cotF | yitD | BL00089 | BL02005 | Spore coat protein F. | (2R)-phospho-3-sulfolactate synthase, ComA. | 0.426 |
| cotH | yitD | BL01316 | BL02005 | Spore coat protein (inner). | (2R)-phospho-3-sulfolactate synthase, ComA. | 0.417 |
| topA | topB | BL01281 | BL02823 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.659 |
| topA | yitD | BL01281 | BL02005 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | (2R)-phospho-3-sulfolactate synthase, ComA. | 0.725 |
| topA | yrhO | BL01281 | BL01292 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Putative cyclodextrin metabolism protein YrhO. | 0.733 |
| topB | topA | BL02823 | BL01281 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.659 |
| topB | yitD | BL02823 | BL02005 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | (2R)-phospho-3-sulfolactate synthase, ComA. | 0.725 |
| topB | yrhO | BL02823 | BL01292 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | Putative cyclodextrin metabolism protein YrhO. | 0.733 |
| yitB | yitD | BL01979 | BL02005 | Phosphoadenosine phosphosulfate reductase CysH-type; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | (2R)-phospho-3-sulfolactate synthase, ComA. | 0.443 |
| yitD | BL00252 | BL02005 | BL00252 | (2R)-phospho-3-sulfolactate synthase, ComA. | Conserved hypothetical protein. | 0.466 |
| yitD | cotF | BL02005 | BL00089 | (2R)-phospho-3-sulfolactate synthase, ComA. | Spore coat protein F. | 0.426 |
| yitD | cotH | BL02005 | BL01316 | (2R)-phospho-3-sulfolactate synthase, ComA. | Spore coat protein (inner). | 0.417 |
| yitD | topA | BL02005 | BL01281 | (2R)-phospho-3-sulfolactate synthase, ComA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.725 |
| yitD | topB | BL02005 | BL02823 | (2R)-phospho-3-sulfolactate synthase, ComA. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.725 |
| yitD | yitB | BL02005 | BL01979 | (2R)-phospho-3-sulfolactate synthase, ComA. | Phosphoadenosine phosphosulfate reductase CysH-type; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.443 |
| yitD | yitG | BL02005 | BL01202 | (2R)-phospho-3-sulfolactate synthase, ComA. | Putative transporter. | 0.434 |
| yitD | yitG-2 | BL02005 | BL01976 | (2R)-phospho-3-sulfolactate synthase, ComA. | Major facilitator superfamily YitG. | 0.632 |
| yitD | yqhV | BL02005 | BL01541 | (2R)-phospho-3-sulfolactate synthase, ComA. | Conserved protein YqhV. | 0.449 |
| yitD | yrhO | BL02005 | BL01292 | (2R)-phospho-3-sulfolactate synthase, ComA. | Putative cyclodextrin metabolism protein YrhO. | 0.618 |