STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bltMultidrug-efflux transporter. (398 aa)    
Predicted Functional Partners:
lmrB
Drug-export protein; Belongs to the major facilitator superfamily.
  
   
 0.689
ykkD
Conserved hypothetical protein YkkD; Probably involved in guanidinium transport.
      
 0.684
bmrA
ABC transporter; Multidrug resistance protein.
  
   
 0.639
ykkC
Putative membrane protein,probable transporter; Probably involved in guanidinium transport.
      
 0.598
yvdT
Probable transcriptional regulator YvdT.
   
  
 0.463
BL02155
C4-dicarboxylate anaerobic carrier.
       0.457
yfiX
Conserved membrane protein YfiX; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
      
 0.430
mtaB
Transcriptional regulator (MerR family); Transcriptional activator of multidrug-efflux transporter genes.
      
 0.427
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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