STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ypdCHypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity). (222 aa)    
Predicted Functional Partners:
rsiW
Antisigma factor RsiW; Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation (By similarity); Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.
  
   
 0.944
yluC
Intramembrane zinc metallopeptidase YluC; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
      
 0.770
yshE
Conserved membrane protein YshE.
  
     0.708
ybeB
Putative metallopeptidase YpeB.
 
     0.694
sleB
Spore cortex-lytic enzyme.
 
     0.640
ansZA
Putative Asparaginase/glutaminase.
       0.599
BL02225
FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
       0.584
hepS
Heptaprenyl diphosphate synthase component I.
  
     0.543
sigW
RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-W); Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.512
cmk
Cytidylate kinase.
       0.488
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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