STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mecBNegative regulator of genetic competence; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. (194 aa)    
Predicted Functional Partners:
clpC
Class III stress response-related ATPase; Belongs to the ClpA/ClpB family.
    
 
 0.793
clpE
ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family.
    
 
 0.772
yjbH
Conserved protein YjbH; Belongs to the UPF0413 family.
   
  
 0.651
ylbO
DNA-binding domain protein.
  
     0.632
blaI
Putative beta-lactamase repressor protein.
      
 0.611
yabA
DnaA and DnaN interacting protein containing domain DUF972- YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.
  
     0.578
comK
Competence transcription factor ComK.
  
   
 0.564
BL02231
Hypothetical protein.
 
     0.529
BL02228
Putative hydrolase.
  
    0.523
yqhG
Conserved protein YqhG.
  
     0.521
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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