STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysGUroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family. (257 aa)    
Predicted Functional Partners:
sirA
Siroheme synthase SirA.
 
 
 0.996
hemC
Porphobilinogen deaminase (hydroxymethylbilane synthase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.994
sirB
Cobalamin (vitamin B12) biosynthesis CbiX protein.
 
 0.986
hemD
Uroporphyrinogen III cosynthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.982
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.957
cysH
Phosphoadenosine phosphosulfate; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.947
sat
Sulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family.
  
  
 0.904
cysJ
Sulfite reductase (NADPH) hemoprotein beta-component CysJ; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.888
hemB
Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family.
 
 
 0.870
BL05279
Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family.
 
 
 0.866
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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