STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hsdMPutative Type I restriction-modification system M subunit. (509 aa)    
Predicted Functional Partners:
hsdS
HsdS.
 
 
 0.997
hsdR
Putative Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.995
BL02383
Hypothetical protein.
 
 
 0.993
hsdSIB
Type I RM system specificity subunit HsdIB.
 
 
 0.977
hsdR1
Type 1 Site Specific deoxyribonuclease protein HsdRI; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.977
hsdIA
Type I Restriction Modification system protein HsdIA.
 
 
 0.925
BL02386
Hypothetical protein.
 
    0.899
BL05391
Hypothetical protein.
 
     0.874
BL02385
Hypothetical protein.
       0.658
uvrB
Excinuclease ABC (subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociat [...]
    
   0.518
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.