| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaC | dnaG | BL01376 | BL03681 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.993 |
| dnaC | hbs | BL01376 | BL02787 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.595 |
| dnaC | topA | BL01376 | BL01281 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.616 |
| dnaG | dnaC | BL03681 | BL01376 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.993 |
| dnaG | hbs | BL03681 | BL02787 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.637 |
| dnaG | rplL | BL03681 | BL02800 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Ribosomal protein L12 (BL9); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.467 |
| dnaG | rplS | BL03681 | BL01290 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.609 |
| dnaG | topA | BL03681 | BL01281 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.600 |
| hbs | dnaC | BL02787 | BL01376 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.595 |
| hbs | dnaG | BL02787 | BL03681 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.637 |
| hbs | mtrA | BL02787 | BL02786 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | GTP cyclohydrolase I. | 0.621 |
| hbs | mtrB | BL02787 | BL02785 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Tryptophan operon RNA-binding attenuation protein (TRAP); Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan. Belongs to the MtrB family. | 0.646 |
| hbs | rplL | BL02787 | BL02800 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein L12 (BL9); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.601 |
| hbs | rplS | BL02787 | BL01290 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.833 |
| hbs | rpsO | BL02787 | BL01219 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein S15 (BS18); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.716 |
| hbs | rpsT | BL02787 | BL02113 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.780 |
| hbs | topA | BL02787 | BL01281 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.613 |
| hbs | yjbQ | BL02787 | BL01593 | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Cation transporter YjbQ; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.763 |
| mtrA | hbs | BL02786 | BL02787 | GTP cyclohydrolase I. | Non-specific DNA-binding protein HBsu signal recognition particle-like (SRP) component; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.621 |
| mtrA | mtrB | BL02786 | BL02785 | GTP cyclohydrolase I. | Tryptophan operon RNA-binding attenuation protein (TRAP); Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan. Belongs to the MtrB family. | 0.810 |
