STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
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[Homology]
Score
ycsKLipolytic enzyme, G-D-S-L; Lipase involved in spore germination; Belongs to the 'GDSL' lipolytic enzyme family. (212 aa)    
Predicted Functional Partners:
ypmS
Conserved protein YpmS.
 
  
 0.829
kipR
Transcriptional regulator KipR.
 
    0.707
yozE
Hypothetical protein; Belongs to the UPF0346 family.
 
  
 0.653
kipA
KipA.
  
    0.617
kipI
Kinase inhibitor KipI.
  
  
 0.615
ycsI
Conserved protein YcsI; Belongs to the D-glutamate cyclase family.
  
    0.533
thyA
Thymidylate synthase A; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.519
ycsF
Putative lactam utilization protein YcsF; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.513
ycsG
Putative branched chain amino acids transporter YcsG.
  
  
 0.490
BL03514
Hypothetical phagelike protein.
  
   0.475
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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