STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hprTranscriptional regulator Hpr; Negative regulator of protease production and sporulation. (206 aa)    
Predicted Functional Partners:
hprK
Serine/threonine protein kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable [...]
    
 
 0.777
ccpA
Transcriptional regulator.
      
 0.774
ywjG
YwjG.
  
     0.762
crh
Catabolite repression protein.
      
 0.758
ypiF
Hypothetical protein.
  
     0.717
yfhH
Conserved protein YfhH.
  
     0.710
yqgB
Conserved membrane protein YqgB.
  
     0.704
ptsH
Histidine-containing phosphocarrier protein of the phosphotransferase system (PTS) (HPr protein).
      
 0.700
yjbL
Conserved protein YjbL; Belongs to the UPF0738 family.
  
     0.699
yufK
Hypothetical protein.
  
     0.694
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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