STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yhcLSodium:dicarboxylate symporter YhcL; Mediates uptake of L-cystine, the oxidized form of L- cysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (461 aa)    
Predicted Functional Partners:
cysI
Sulfite reductase (NADPH) flavoprotein alpha-component CysI; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
   
  
 0.742
cysJ
Sulfite reductase (NADPH) hemoprotein beta-component CysJ; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
  
 0.690
cypE
Cytochrome P450 / NADPH-ferrihemoprotein reductase; In the N-terminal section; belongs to the cytochrome P450 family.
   
  
 0.681
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
   
    0.665
cysK
Cysteine synthetase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  
 0.643
braB
Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids.
  
   
 0.602
cysP
Sulfate permease.
   
  
 0.580
ydeD
Putative membrane protein, transporter.
      
 0.573
metP
Binding-protein-dependent transport systems inner membrane component.
      
 0.543
ydhG
Hypothetical protein.
      
 0.540
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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