| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| clpC | clpP | BL03261 | BL03605 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | 0.980 |
| clpC | clpP2 | BL03261 | BL05355 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | ATP-dependentprotease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.872 |
| clpC | ctsR | BL03261 | BL03258 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Transcriptional regulator; Belongs to the CtsR family. | 0.995 |
| clpC | disA | BL03261 | BL03263 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | DNA binding protein; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.737 |
| clpC | mcsA | BL03261 | BL03259 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | McsA. | 0.996 |
| clpC | mcsB | BL03261 | BL03260 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | McsB; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | 0.999 |
| clpC | radA | BL03261 | BL03262 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.882 |
| clpC | yacL | BL03261 | BL03264 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Conserved hypothetical protein YacL; Putative Nucleotide binding protein, PINc. | 0.685 |
| clpC | ywlE | BL03261 | BL03988 | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Low molecular weight phosphotyrosine protein phosphatase. | 0.447 |
| clpE | clpP | BL03640 | BL03605 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | 0.976 |
| clpE | clpP2 | BL03640 | BL05355 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | ATP-dependentprotease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.876 |
| clpE | ctsR | BL03640 | BL03258 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | Transcriptional regulator; Belongs to the CtsR family. | 0.879 |
| clpE | mcsA | BL03640 | BL03259 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | McsA. | 0.789 |
| clpE | mcsB | BL03640 | BL03260 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | McsB; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | 0.915 |
| clpE | radA | BL03640 | BL03262 | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.412 |
| clpP | clpC | BL03605 | BL03261 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | Class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | 0.980 |
| clpP | clpE | BL03605 | BL03640 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | ATP-dependent Clp protease-like (class III stress gene) ClpE; Belongs to the ClpA/ClpB family. | 0.976 |
| clpP | clpP2 | BL03605 | BL05355 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | ATP-dependentprotease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.547 |
| clpP | ctsR | BL03605 | BL03258 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | Transcriptional regulator; Belongs to the CtsR family. | 0.735 |
| clpP | mcsA | BL03605 | BL03259 | ATP-dependent Clp protease proteolytic subunit (class III heat-shock protein); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. ClpXP1 is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity); Belongs to the peptidase S14 family. | McsA. | 0.694 |
