| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ezrA | pbpH | BL00433 | BL03575 | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Penicillin-binding Protein dimerisation domain. | 0.771 |
| ezrA | ppnK1 | BL00433 | BL05111 | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.491 |
| ezrA | yjbH | BL00433 | BL03343 | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Conserved protein YjbH; Belongs to the UPF0413 family. | 0.740 |
| ezrA | yjbK | BL00433 | BL03346 | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Conserved protein YjbK. | 0.686 |
| ezrA | ypsB | BL00433 | BL05235 | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Conserved hypothetical protein YpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.943 |
| ezrA | yvlB | BL00433 | BL03397 | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | Conserved hypothetical protein YvlB. | 0.408 |
| ispAB | yjbK | BL01524 | BL03346 | Polyprenyl synthetase,Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Conserved protein YjbK. | 0.550 |
| pbpH | ezrA | BL03575 | BL00433 | Penicillin-binding Protein dimerisation domain. | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.771 |
| pbpH | yjbK | BL03575 | BL03346 | Penicillin-binding Protein dimerisation domain. | Conserved protein YjbK. | 0.538 |
| pbpH | ypsB | BL03575 | BL05235 | Penicillin-binding Protein dimerisation domain. | Conserved hypothetical protein YpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.779 |
| ppnK1 | ezrA | BL05111 | BL00433 | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.491 |
| ppnK1 | yjbH | BL05111 | BL03343 | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Conserved protein YjbH; Belongs to the UPF0413 family. | 0.526 |
| ppnK1 | yjbJ | BL05111 | BL03345 | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Putative Glycoside Hydrolase Family 23, YjbJ. | 0.514 |
| ppnK1 | yjbK | BL05111 | BL03346 | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Conserved protein YjbK. | 0.630 |
| ppnK1 | yjbL | BL05111 | BL05110 | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Conserved protein YjbL; Belongs to the UPF0738 family. | 0.760 |
| ppnK1 | ypsB | BL05111 | BL05235 | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Conserved hypothetical protein YpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.620 |
| yjbH | ezrA | BL03343 | BL00433 | Conserved protein YjbH; Belongs to the UPF0413 family. | EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.740 |
| yjbH | ppnK1 | BL03343 | BL05111 | Conserved protein YjbH; Belongs to the UPF0413 family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.526 |
| yjbH | yjbJ | BL03343 | BL03345 | Conserved protein YjbH; Belongs to the UPF0413 family. | Putative Glycoside Hydrolase Family 23, YjbJ. | 0.549 |
| yjbH | yjbK | BL03343 | BL03346 | Conserved protein YjbH; Belongs to the UPF0413 family. | Conserved protein YjbK. | 0.622 |