STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family (430 aa)    
Predicted Functional Partners:
pgk
Molecular Function: phosphoglycerate kinase activity, Biological Process: glycolysis; Belongs to the phosphoglycerate kinase family
 
 
 0.999
pyk
Molecular Function: pyruvate kinase activity, Biological Process: glycolysis; Belongs to the pyruvate kinase family
 
 0.997
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family
 
 
 0.997
pgm
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate
  
 
 0.997
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Catabolic enzyme, Biological Process: glucose metabolism, Molecular Function: glyceraldehyde-3-phosphate dehydrogenase activity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
 
 
 0.989
pgi
Molecular Function: glucose-6-phosphate isomerase activity, Biological Process: gluconeogenesis, Biological Process: glycolysis
  
 0.987
gapB
Glyceraldehyde-3-phosphate dehydrogenase; Anabolic enzyme, Biological Process: glucose metabolism, Molecular Function: glyceraldehyde-3-phosphate dehydrogenase activity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
 
 
 0.977
fbaA
Molecular Function: fructose-bisphosphate aldolase activity, Biological Process: glycolysis, Molecular Function: zinc ion binding
  
 
 0.967
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
 
 0.962
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
   
 
 0.948
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis DSM13
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