| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BL01924 | queC | BL01924 | BL03546 | Putative ribonucleoside-triphosphate reductase activating protein. | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.775 |
| BL01924 | queD | BL01924 | BL03547 | Putative ribonucleoside-triphosphate reductase activating protein. | 6-pyruvoyl tetrahydropterin synthase QueD. | 0.852 |
| BL01924 | queF | BL01924 | BL03549 | Putative ribonucleoside-triphosphate reductase activating protein. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.724 |
| BL02467 | queC | BL02467 | BL03546 | Iron-binding, putative oxidoreductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.775 |
| BL02467 | queD | BL02467 | BL03547 | Iron-binding, putative oxidoreductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 6-pyruvoyl tetrahydropterin synthase QueD. | 0.852 |
| BL02467 | queF | BL02467 | BL03549 | Iron-binding, putative oxidoreductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.724 |
| cysH | queC | BL02282 | BL03546 | Phosphoadenosine phosphosulfate; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.674 |
| cysH | yitB | BL02282 | BL01979 | Phosphoadenosine phosphosulfate; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | Phosphoadenosine phosphosulfate reductase CysH-type; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.557 |
| glmS | murD | BL02704 | BL02241 | L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylmuramoylalanyl-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.412 |
| glmS | queC | BL02704 | BL03546 | L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.555 |
| glmS | queD | BL02704 | BL03547 | L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 6-pyruvoyl tetrahydropterin synthase QueD. | 0.420 |
| glmS | queE | BL02704 | BL03548 | L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.616 |
| glmS | queF | BL02704 | BL03549 | L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.560 |
| murD | glmS | BL02241 | BL02704 | UDP-N-acetylmuramoylalanyl-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.412 |
| murD | queC | BL02241 | BL03546 | UDP-N-acetylmuramoylalanyl-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.582 |
| queC | BL01924 | BL03546 | BL01924 | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | Putative ribonucleoside-triphosphate reductase activating protein. | 0.775 |
| queC | BL02467 | BL03546 | BL02467 | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | Iron-binding, putative oxidoreductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.775 |
| queC | cysH | BL03546 | BL02282 | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | Phosphoadenosine phosphosulfate; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.674 |
| queC | glmS | BL03546 | BL02704 | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.555 |
| queC | murD | BL03546 | BL02241 | Queuosine (Q) synthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | UDP-N-acetylmuramoylalanyl-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.582 |