STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pbpAPenicillin-binding protein 2A. (705 aa)    
Predicted Functional Partners:
rodA
RodA; Belongs to the SEDS family.
 
 
 0.898
divIB
Cell-division initiation protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
 
 0.873
mreC
Cell-shape determining protein; Involved in formation and maintenance of cell shape.
 
 
 0.863
BL03883
Cell division protein; Belongs to the SEDS family.
 
 
 0.844
ponA
Penicillin-binding proteins,Glycosyl Transferase Family 51.
  
 
 0.841
murC
UDP-N-acetyl muramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
 0.825
ftsW
Cell-division protein; Belongs to the SEDS family.
 
 
 0.814
prkC
Protein kinase PrkC.
 
  
 0.794
ypsB
Conserved hypothetical protein YpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
 
  
 0.787
ezrA
EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
   
 0.782
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.