STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adaAmethylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family). (186 aa)    
Predicted Functional Partners:
adaB
O6-methylguanine-DNA methyltransferase.
  
 0.999
ogt
O6-methylguanine DNA alkyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
 0.971
yfjP
Putative DNA glycosylase; Similar to DNA-3-methyladenine glycosidase II.
   
 0.939
yxlJ
Methylpurine-DNA glycosylase (MPG); Belongs to the DNA glycosylase MPG family.
  
  
 0.662
comEC
ComEC.
     
 0.631
cinA
Competence-damage inducible protein; Belongs to the CinA family.
     
 0.590
glmS
L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.540
cat
Antibiotic resistance protein, methyltransferase; This enzyme is an effector of chloramphenicol resistance in bacteria; Belongs to the chloramphenicol acetyltransferase family.
       0.482
ndhF
NADH dehydrogenase (subunit 5).
      
 0.457
sigA
RNA polymerase major sigma-43 factor (sigma-A); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.434
Your Current Organism:
Bacillus licheniformis
NCBI taxonomy Id: 279010
Other names: B. licheniformis DSM 13 = ATCC 14580, Bacillus licheniformis ATCC 14580, Bacillus licheniformis ATCC 14580 = DSM 13, Bacillus licheniformis DSM 13, Bacillus licheniformis DSM 13 = ATCC 14580
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