node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BL00458 | nadD | BL00458 | BL02081 | Hypothetical protein. | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.605 |
BL00458 | nadE | BL00458 | BL01706 | Hypothetical protein. | NH3-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.583 |
BL00458 | npdA | BL00458 | BL02876 | Hypothetical protein. | NdpA; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.738 |
BL00458 | yhcX | BL00458 | BL03168 | Hypothetical protein. | Conserved hypothetical protein YhcX. | 0.529 |
BL00458 | yueK | BL00458 | BL02611 | Hypothetical protein. | Nicotinate phosphoribosyltransferase related; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.595 |
aroK | nadE | BL01707 | BL01706 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | NH3-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.619 |
cinA | coaD | BL05163 | BL02991 | Competence-damage inducible protein; Belongs to the CinA family. | Coenzyme A biosynthesis protein,Cytidyltransferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.442 |
cinA | nadD | BL05163 | BL02081 | Competence-damage inducible protein; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.899 |
cinA | nadE | BL05163 | BL01706 | Competence-damage inducible protein; Belongs to the CinA family. | NH3-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.724 |
cinA | npdA | BL05163 | BL02876 | Competence-damage inducible protein; Belongs to the CinA family. | NdpA; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.714 |
cinA | ppnK1 | BL05163 | BL05111 | Competence-damage inducible protein; Belongs to the CinA family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.534 |
cinA | ppnK2 | BL05163 | BL00367 | Competence-damage inducible protein; Belongs to the CinA family. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.534 |
cinA | yhcX | BL05163 | BL03168 | Competence-damage inducible protein; Belongs to the CinA family. | Conserved hypothetical protein YhcX. | 0.544 |
cinA | yueK | BL05163 | BL02611 | Competence-damage inducible protein; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase related; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.866 |
coaD | cinA | BL02991 | BL05163 | Coenzyme A biosynthesis protein,Cytidyltransferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Competence-damage inducible protein; Belongs to the CinA family. | 0.442 |
coaD | nadD | BL02991 | BL02081 | Coenzyme A biosynthesis protein,Cytidyltransferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.734 |
coaD | nadE | BL02991 | BL01706 | Coenzyme A biosynthesis protein,Cytidyltransferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | NH3-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.612 |
coaD | npdA | BL02991 | BL02876 | Coenzyme A biosynthesis protein,Cytidyltransferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | NdpA; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.508 |
coaD | ppnK1 | BL02991 | BL05111 | Coenzyme A biosynthesis protein,Cytidyltransferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.510 |
coaD | ppnK2 | BL02991 | BL00367 | Coenzyme A biosynthesis protein,Cytidyltransferase-related domain; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.510 |