Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lapBTPR repeat family protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (391 aa)    
Predicted Functional Partners:
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
  
 
 
 0.825
AMP06898.1
Hypothetical protein.
 
   
 0.762
AMP06655.1
Putative permease YjgP/YjgQ family protein.
 
   
 0.738
lptD
Organic solvent tolerance family protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
   
 0.696
AMP06896.1
Nucleotide sugar dehydrogenase family protein.
       0.671
rfaE
Bifunctional protein RfaE, domain I.
       0.616
lpxH
UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
     0.608
AMP03408.1
Putative membrane protein.
  
     0.587
ftsB
Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
 
     0.569
bamE
smpA / OmlA family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.569
Your Current Organism:
Collimonas pratensis
NCBI taxonomy Id: 279113
Other names: C. pratensis, CCUG 54728, Collimonas group D, Collimonas pratensis Hoppener-Ogawa et al. 2008, Collimonas sp. CTO 113, Collimonas sp. CTO 291, Collimonas sp. CTO 90, Collimonas sp. CTO 91, Collimonas sp. CTO 94, Collimonas sp. Ter113, Collimonas sp. Ter118, Collimonas sp. Ter227, Collimonas sp. Ter291, Collimonas sp. Ter90, Collimonas sp. Ter91, Collimonas sp. Ter94, LMG 23965, LMG:23965, strain Ter91
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.