Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (468 aa)    
Predicted Functional Partners:
Saro_2409
Methionine synthase, vitamin-B12 independent.
  
 
 0.958
Saro_3207
Methionine synthase (B12-dependent).
  
 
 0.942
metZ
Cystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.940
Saro_3206
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.939
Saro_2554
Cystathionine beta-lyase.
  
 0.923
Saro_0813
O-acetylhomoserine sulfhydrolase.
     
 0.913
Saro_3294
MTA/SAH nucleosidase family protein.
    
 0.911
Saro_1061
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 0.839
Saro_1121
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 0.839
Saro_2103
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.839
Your Current Organism:
Novosphingobium aromaticivorans
NCBI taxonomy Id: 279238
Other names: N. aromaticivorans DSM 12444, Novosphingobium aromaticivorans DSM 12444, Novosphingobium aromaticivorans str. DSM 12444, Novosphingobium aromaticivorans strain DSM 12444
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