Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (387 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
 0.998
argD
Acetylornithine aminotransferase; Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
 0.992
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
 
 0.988
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.966
APT86774.1
Acetylglutamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.954
APT86772.1
N-acetyl-gamma-glutamyl-phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.926
APT87133.1
Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.921
argR
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.919
APT87678.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.910
APT87733.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.901
Your Current Organism:
Corynebacterium flavescens
NCBI taxonomy Id: 28028
Other names: ATCC 10340, C. flavescens, CCUG 28791, CIP 69.5, DSM 20296, IFO 14136, LMG 4046, LMG:4046, Microbacterium flavum , Mycobacterium flavum, NBRC 14136, NCCB 42012, NCIB 8707, NCIB:8707, NCIMB 8707
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