STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CQ12_12835Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 0.895
CQ12_33385
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.806
CQ12_35590
Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.801
CQ12_02960
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.766
CQ12_02610
Inosine-5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.715
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.712
CQ12_12830
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.699
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.694
CQ12_35110
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.673
CQ12_31545
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.658
Your Current Organism:
Bradyrhizobium jicamae
NCBI taxonomy Id: 280332
Other names: B. jicamae, Bradyrhizobium jicamae Ramirez-Bahena et al. 2009, Bradyrhizobium sp. PAC68, Bradyrhizobium sp. PAC683, Bradyrhizobium sp. PAC684, CECT 7395, LMG 24556, LMG:24556, strain PAC68
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