STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CQ12_18495Precorrin 6A synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. (249 aa)    
Predicted Functional Partners:
CQ12_18515
Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
 
 0.997
CQ12_18530
cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
CQ12_18525
precorrin-6Y methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.994
cobH
Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.990
CQ12_18520
Precorrin methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
CQ12_18535
Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
CQ12_18550
precorrin-3B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.917
CQ12_18510
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.870
CQ12_33915
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
    
 0.855
cobQ
Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.841
Your Current Organism:
Bradyrhizobium jicamae
NCBI taxonomy Id: 280332
Other names: B. jicamae, Bradyrhizobium jicamae Ramirez-Bahena et al. 2009, Bradyrhizobium sp. PAC68, Bradyrhizobium sp. PAC683, Bradyrhizobium sp. PAC684, CECT 7395, LMG 24556, LMG:24556, strain PAC68
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.