Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OLZ19684.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (345 aa)    
Predicted Functional Partners:
OLZ22059.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
  0.942
OLZ18089.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.782
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.761
OLZ18112.1
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.750
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.725
OLZ22108.1
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.709
OLZ21043.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.677
OLZ20493.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.677
OLZ19685.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.561
OLZ18385.1
O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.468
Your Current Organism:
Sulfobacillus thermosulfidooxidans
NCBI taxonomy Id: 28034
Other names: DSM 9293, S. thermosulfidooxidans, Sulfobacillus sp. G2, strain AT-1
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