node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANY12707.1 | ANY13409.1 | BCY75_00975 | BCY75_05165 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.939 |
ANY12707.1 | polA | BCY75_00975 | BCY75_05140 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.737 |
ANY12961.1 | ANY13409.1 | BCY75_02445 | BCY75_05165 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family. | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.676 |
ANY12961.1 | dnaB_2 | BCY75_02445 | BCY75_05160 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family. | Helicase DnaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.664 |
ANY12961.1 | dnaD | BCY75_02445 | BCY75_07435 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family. | DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
ANY12961.1 | ezrA | BCY75_02445 | BCY75_07060 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family. | Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.603 |
ANY12961.1 | recU | BCY75_02445 | BCY75_07450 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family. | Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.475 |
ANY13409.1 | ANY12707.1 | BCY75_05165 | BCY75_00975 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.939 |
ANY13409.1 | ANY12961.1 | BCY75_05165 | BCY75_02445 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family. | 0.676 |
ANY13409.1 | coaE | BCY75_05165 | BCY75_05150 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.660 |
ANY13409.1 | dnaB_2 | BCY75_05165 | BCY75_05160 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase DnaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.965 |
ANY13409.1 | dnaD | BCY75_05165 | BCY75_07435 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.838 |
ANY13409.1 | ezrA | BCY75_05165 | BCY75_07060 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. | 0.691 |
ANY13409.1 | mutM | BCY75_05165 | BCY75_05145 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.773 |
ANY13409.1 | nrdR | BCY75_05165 | BCY75_05155 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes. | 0.812 |
ANY13409.1 | polA | BCY75_05165 | BCY75_05140 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.805 |
ANY13409.1 | recU | BCY75_05165 | BCY75_07450 | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.668 |
coaE | ANY13409.1 | BCY75_05150 | BCY75_05165 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.660 |
coaE | dnaB_2 | BCY75_05150 | BCY75_05160 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Helicase DnaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.651 |
coaE | mutM | BCY75_05150 | BCY75_05145 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.995 |