STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GU90_00535Virulence protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)    
Predicted Functional Partners:
GU90_10270
methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.679
GU90_10275
methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.679
GU90_07740
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.652
GU90_07100
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.603
nuoI
Ferredoxin; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 
 0.576
GU90_08520
Threonine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.574
GU90_00865
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.502
GU90_16705
Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.502
GU90_00420
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.499
GU90_03525
Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.498
Your Current Organism:
Saccharopolyspora rectivirgula
NCBI taxonomy Id: 28042
Other names: ATCC 33515, DSM 43747, Faenia rectivirgula, IFO 12464, INMI 683, JCM 3057, Micropolyspora faeni, Micropolyspora rectivirgula, NBRC 12464, NRRL B-16280, S. rectivirgula, Thermopolyspora polyspora, Thermopolyspora rectivirgula, VKM Ac-810
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.