STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GU90_01375Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)    
Predicted Functional Partners:
GU90_01370
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.608
katE
Hydroperoxidase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
  
 0.605
GU90_01365
F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.563
GU90_01360
Branched-chain amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.516
GU90_15150
Ferritin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family.
  
  
 0.508
grpE
Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]
      
 0.454
GU90_05595
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.424
GU90_14270
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.410
GU90_14945
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0337 (CsbD) family.
   
    0.408
Your Current Organism:
Saccharopolyspora rectivirgula
NCBI taxonomy Id: 28042
Other names: ATCC 33515, DSM 43747, Faenia rectivirgula, IFO 12464, INMI 683, JCM 3057, Micropolyspora faeni, Micropolyspora rectivirgula, NBRC 12464, NRRL B-16280, S. rectivirgula, Thermopolyspora polyspora, Thermopolyspora rectivirgula, VKM Ac-810
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