Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppnKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (297 aa)    
Predicted Functional Partners:
GU90_01935
Cytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.934
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.933
GU90_01945
DNA recombination protein RecN; May be involved in recombinational repair of damaged DNA.
   
 0.930
GU90_13130
NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.822
GU90_10205
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.800
GU90_16330
NADH pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.795
GU90_01930
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.790
GU90_01925
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.752
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
    
 0.738
GU90_04195
Nucleoside-triphosphate diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.678
Your Current Organism:
Saccharopolyspora rectivirgula
NCBI taxonomy Id: 28042
Other names: ATCC 33515, DSM 43747, Faenia rectivirgula, IFO 12464, INMI 683, JCM 3057, Micropolyspora faeni, Micropolyspora rectivirgula, NBRC 12464, NRRL B-16280, S. rectivirgula, Thermopolyspora polyspora, Thermopolyspora rectivirgula, VKM Ac-810
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.