Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pxpAHypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (253 aa)    
Predicted Functional Partners:
GU90_04495
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
GU90_04490
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
GU90_04505
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.941
GU90_04485
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-glutamate cyclase family.
 
    0.910
GU90_07560
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.804
GU90_10005
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.804
GU90_04320
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
   
 
  0.797
GU90_10750
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.797
gsr10
1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.795
purQ
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
     
  0.795
Your Current Organism:
Saccharopolyspora rectivirgula
NCBI taxonomy Id: 28042
Other names: ATCC 33515, DSM 43747, Faenia rectivirgula, IFO 12464, INMI 683, JCM 3057, Micropolyspora faeni, Micropolyspora rectivirgula, NBRC 12464, NRRL B-16280, S. rectivirgula, Thermopolyspora polyspora, Thermopolyspora rectivirgula, VKM Ac-810
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