STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GU90_10605Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)    
Predicted Functional Partners:
GU90_10600
Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.896
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
 0.859
GU90_10595
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.821
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
  
  
 0.796
GU90_00405
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.762
GU90_02895
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.741
GU90_05225
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.740
GU90_09050
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.729
GU90_04405
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.715
GU90_15395
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.711
Your Current Organism:
Saccharopolyspora rectivirgula
NCBI taxonomy Id: 28042
Other names: ATCC 33515, DSM 43747, Faenia rectivirgula, IFO 12464, INMI 683, JCM 3057, Micropolyspora faeni, Micropolyspora rectivirgula, NBRC 12464, NRRL B-16280, S. rectivirgula, Thermopolyspora polyspora, Thermopolyspora rectivirgula, VKM Ac-810
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