Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GU90_13765acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)    
Predicted Functional Partners:
GU90_04620
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.999
GU90_04605
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
GU90_07430
acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
GU90_12330
acetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
fabH
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.994
GU90_06925
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.993
GU90_06935
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.993
GU90_07245
Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.993
GU90_13080
enoyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.985
GU90_13770
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.934
Your Current Organism:
Saccharopolyspora rectivirgula
NCBI taxonomy Id: 28042
Other names: ATCC 33515, DSM 43747, Faenia rectivirgula, IFO 12464, INMI 683, JCM 3057, Micropolyspora faeni, Micropolyspora rectivirgula, NBRC 12464, NRRL B-16280, S. rectivirgula, Thermopolyspora polyspora, Thermopolyspora rectivirgula, VKM Ac-810
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.