| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ORV09996.1 | ORV17997.1 | AWB95_17455 | AWB95_04000 | Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | 0.662 |
| ORV09996.1 | ORV18162.1 | AWB95_17455 | AWB95_05105 | Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.571 |
| ORV09996.1 | thiG | AWB95_17455 | AWB95_18545 | Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.529 |
| ORV09996.1 | thiI | AWB95_17455 | AWB95_04400 | Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.480 |
| ORV15296.1 | ORV18162.1 | AWB95_07320 | AWB95_05105 | rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.525 |
| ORV15296.1 | mnmA | AWB95_07320 | AWB95_05110 | rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA(5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.463 |
| ORV15296.1 | thiI | AWB95_07320 | AWB95_04400 | rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.825 |
| ORV17997.1 | ORV09996.1 | AWB95_04000 | AWB95_17455 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.662 |
| ORV17997.1 | ORV18162.1 | AWB95_04000 | AWB95_05105 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.972 |
| ORV17997.1 | ORV19040.1 | AWB95_04000 | AWB95_01885 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.734 |
| ORV17997.1 | egtE | AWB95_04000 | AWB95_19640 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Ergothioneine biosynthesis PLP-dependent enzyme EgtE; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.662 |
| ORV17997.1 | mnmA | AWB95_04000 | AWB95_05110 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | tRNA(5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.527 |
| ORV17997.1 | thiG | AWB95_04000 | AWB95_18545 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.992 |
| ORV17997.1 | thiI | AWB95_04000 | AWB95_04400 | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.821 |
| ORV18162.1 | ORV09996.1 | AWB95_05105 | AWB95_17455 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase class V; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.571 |
| ORV18162.1 | ORV15296.1 | AWB95_05105 | AWB95_07320 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.525 |
| ORV18162.1 | ORV17997.1 | AWB95_05105 | AWB95_04000 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molybdopterin biosynthesis-like protein MoeZ; The proteins in this cluster have high sequence similarity to MoeB and are possibly involved in the synthesis of molybdopterin, but there has been no biochemical or physiological characterization. There is also no genetic linkage to other molybdopterin cofactor synthesis proteins. These proteins are similar to a Pseudomonas stutzeri protein which is essential to pyridine-2,6-bis(thiocarboxylic acid) synthesis that possibly activates a substrate by adenylation; Derived by automated computational analysis using gene prediction method: Protein [...] | 0.972 |
| ORV18162.1 | ORV18261.1 | AWB95_05105 | AWB95_04075 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cyclodehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.776 |
| ORV18162.1 | ORV19040.1 | AWB95_05105 | AWB95_01885 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.860 |
| ORV18162.1 | egtE | AWB95_05105 | AWB95_19640 | Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ergothioneine biosynthesis PLP-dependent enzyme EgtE; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.773 |
